In the era of the COVID-19 pandemic, the use virtual learning has been increasingly ubiquitous. In particular, diverse apps has been developed to cater for the demands of many universities and schools. In Vinh University, Zoom is one of the most commonplace software which has been used throughout the last 2 school years. This study has been conducted in an attempt to find out the effects of translation teaching and learning through Zoom software on non-english majored students' performances. 30 English non-major students at Vinh University involved voluntarily in the study for 10 weeks of treatment. The data were collected from 10 zoom recordings, interviews and teacher's observation notes. After the data analysis, the results indicated that the Zoom-based lessons helped improve students' interaction confidence, translation fluency and searching strategies. Based on the findings, a number of implications were put forward for a better application in online translation classrooms.